What is CBG: Exploring the Entourage Effect

The Entourage Effect: The Synergy of CBD and Cannabinoids
What is CBD? What is CBN? Will they get me high? What about CBC? What is CBG? Can I take them together? What is the entourage effect and how does it work? If you have asked yourself a couple of these questions – you’re in the right place!
Cannabidiol (CBD) has recently gained popularity for its potential health benefits. Unlike THC (tetrahydrocannabinol), CBD does not produce a “high,” and can be commonly used for pain management. Known for its calming effects, CBD can help with conditions such as chronic pain, arthritis, and muscle soreness. Many of our customers use CBD to help with sleep. Beyond that, CBD has anti-inflammatory properties that may help with conditions like arthritis.
Research also suggests it may offer neuroprotective benefits for individuals with Alzheimer’s, Parkinson’s, and multiple sclerosis. Additionally, CBD is being studied for its potential role in supporting heart health by lowering blood pressure and reducing the risk of heart disease. Some evidence indicates it could help manage addiction by reducing cravings for substances like nicotine, opioids, and alcohol. CBD is non-psychoactive, providing therapeutic benefits without intoxicating effects. It is generally well-tolerated making it an attractive natural alternative to pharmaceuticals.
Meet the Bliss Molecule: Anandamide & Its Role in the ECS
A key player in this system is anandamide, often referred to as the “bliss molecule.” Anandamide is a naturally occurring neurotransmitter that binds to cannabinoid receptors, much like THC, but is produced by the body. It plays a vital role in regulating mood, stress, and pain, contributing to the feeling of well-being and relaxation.
Unlike THC, which strongly binds to CB1 receptors and produces long-lasting psychoactive effects, anandamide is quickly broken down by the enzyme FAAH (fatty acid amide hydrolase). However, compounds like CBD may help prevent this breakdown, allowing anandamide to stay in the system longer and prolong its mood-boosting and stress-relieving effects. This is why many users report a sense of calm and balance when using CBD—it indirectly supports the body’s natural production of the bliss molecule.
Activities like exercise (often associated with a “runner’s high”), meditation, and even eating dark chocolate have been shown to increase anandamide levels naturally. When combined with cannabinoids like CBD, CBG, and CBC, the result can be an even greater sense of relaxation, focus, and overall well-being—further enhancing the entourage effect.
Exploring CBG, CBN, and CBD
Ever heard the term “better together”? Think about CBD and cannabigerol (CBG), cannabinol (CBN), and cannabichromene (CBC) as a team working together to interact with one another to maximize a wide range of benefits. The entourage effect discerns that combining cannabinoids may enhance their effects, offering full-spectrum benefits. Cannabinol (CBN), cannabigerol (CBG), and cannabichromene (CBC) are lesser-known cannabinoids found in the cannabis plant, each exhibiting unique potential therapeutic properties. When combined, these compounds may contribute to the “entourage effect,” a proposed mechanism where multiple cannabis constituents work synergistically to enhance overall therapeutic outcomes.
Each of these cannabinoids—CBC, CBG, CBN, and CBD—has distinct properties and effects. These cannabinoids interact with the endocannabinoid system (ECS) in different ways.
Here’s a breakdown of their key differences:
EFFECTS |
BENEFITS |
USES |
|
CBC (Cannabichromene) |
Non-psychoactive; interacts with CB2 receptors and transient receptor potential (TRP) channels rather than CB1 receptors. |
Anti-inflammatory Pain relief (synergistic with THC and other cannabinoids) Antidepressant properties Neuroprotective effects |
Research suggests it may help with pain, mood disorders, and neuroprotection. |
CBG (Cannabigerol) |
Non-psychoactive; considered the “mother of all cannabinoids” because it serves as the precursor to THC, CBD, and CBC. |
Anti-inflammatory (may help with colitis and IBD) Neuroprotective (potential for Huntington’s and Parkinson’s disease) Antibacterial properties (studies suggest it may help fight MRSA) May promote appetite stimulation |
Found in broad- and full-spectrum hemp extracts; growing interest in its potential therapeutic effects. |
CBN (cannabinol) |
Mildly psychoactive (much weaker than THC); forms as THC degrades |
Sedative properties (sleep aid) Pain relief Anti-inflammatory |
Sleep aid and relaxation, often combined with CBD and terpenes. |
Everyday Edibles For Everybody.
Whether you’re a pro or a newbie, at Seventh Hill CBD we believe there can truly be a daily edible for everybody. From anxiety relief and non-psychoactive ingredients to a full body buzz, we’ve got just the experience and range of effects you may be looking for. By combining cannabinoids through handcrafted, delicious goodies, you can maximize benefits or give yourself the pain relief boost you may need.
While each cannabinoid has individual benefits, combining them with other cannabinoids and terpenes may enhance their effects. This synergy, called the entourage effect, suggests that full-spectrum cannabis extracts may be more effective than isolated cannabinoids alone. The entourage effect is a crucial concept in cannabinoid science, referring to how cannabinoids work better together than alone. When CBC is combined with CBD, CBN, or CBG, the results can be even more profound:
- CBC + CBD: Enhances CBD’s pain-relieving and anti-inflammatory properties, making it more effective for chronic pain and inflammation.
- Try our White Peach CBC Gummies with CBD Hawaiian Alaea Salt Caramels
- CBC + CBN: May improve sleep quality and relaxation, amplifying the calming effects of CBN.
- Try our 1:1 THC:CBN Sleep Gummies with our White Peach CBC Gummies.
- CBC + CBG: Could support brain function and neuroprotection, as both cannabinoids show potential in promoting cognitive health.
- Try our Micro-Cannabinoid Bundle.
While science behind cannabinoids is evolving, the entourage effect proves that these compounds work better together. By combining CBD with CBC, CBG, and CBN, you can tailor your desired experience to be enhanced with benefits for pain relief, sleep, inflammation, mood support, and much more. Whether you’re looking to relax, improve focus, or find natural alternatives for health concerns, full-spectrum and broad-spectrum products offer a way to harness the full potential of hemp-derived cannabinoids.
Seventh Hill CBD handcrafts everyday edibles in small batches to bring you a wide range of potencies + effects, allowing you to Rise, Inspire, Unwind, or Let It Be. As always, we’re here to help you find the perfect edible for everybody – if you need recommendations, don’t hesitate to contact us!